Question for the Nurses-Current or Retired

I’ve been trying to figure the dosing/quantities in the 10mcg Byetta
pen. Doesn’t make sense to me and maybe someone can show me where I am
going astray.

On the pen it says: 60 subcutanious doses of 10mcg per pen. That’s
about 1.6u per 10mcg shot. But, it also says (quantity) 250mcg/ml, 2.4ml
on the pen. 60 x 10mcg = 600mcg???

11 Responses to “Question for the Nurses-Current or Retired”

  1. Neva Marjory Says:

    not sure what you are asking but a 10 mcg dose is 4 units on a normal
    syringe. 5 mch would be 2 units, etc.

    I’ve been trying to figure the dosing/quantities in the 10mcg Byetta
    pen. Doesn’t make sense to me and maybe someone can show me where I am
    going astray.

    On the pen it says: 60 subcutanious doses of 10mcg per pen. That’s
    about 1.6u per 10mcg shot. But, it also says (quantity) 250mcg/ml, 2.4ml
    on the pen. 60 x 10mcg = 600mcg???

    5mcg should equal .8333333u/ml, 10mcg =1.6u/ml, 15mcg would equal 2 1/2
    u/ml. Does that look right?

    100u = 3ml.

    Any ideas?


    Dave - 4:21:44 PM

    [Non-text portions of this message have been removed]

  2. Dwain Palmer Says:

    Ok, that’s exactly what I’m looking for-a conversion of a 5mcg dose to
    units, and also the 10mcg.

    What has me really confused is the Symlin dose conversion chart
    available on their web site. I think some are on Symlin here.

    It says 15 micrograms = 2 1/2 units
    30 micrograms = 5 units.

    So, as you can see there is a difference in what you said and that’s
    what I am trying to figure out. Which is correct? Say using a BD 1/2 CC
    syringe.

  3. Neva Marjory Says:

    using a normal BD syringe, and dosing mcg to the unit lines on the normal
    syringe you get 4 cc’s per 10 mcg dose. so it would be 2 or half for the 5
    mcg dose. don’t know what math is as i just spent the dose out and used a
    syringe to lap it back up :)
    jodi

    Ok, that’s exactly what I’m looking for-a conversion of a 5mcg dose to
    units, and also the 10mcg.

    What has me really confused is the Symlin dose conversion chart
    available on their web site. I think some are on Symlin here.

    It says 15 micrograms = 2 1/2 units
    30 micrograms = 5 units.

    So, as you can see there is a difference in what you said and that’s
    what I am trying to figure out. Which is correct? Say using a BD 1/2 CC
    syringe.

    [Non-text portions of this message have been removed]

  4. Whitney Shamika Says:

    Dave, a microgram is a noun and is equal to 1/1000 of a milligram, as below one
    millionth of a gram. Can you figure it out now? My math leaves my brain, I
    will try to figure it out.
    Frances
    NOUN: A unit of mass equal to one thousandth (10- 3 ) of a milligram or one
    millionth (10- 6 ) of a gram.

    On the pen it says: 60 subcutanious doses of 10mcg per pen. That’s
    about 1.6u per 10mcg shot. But, it also says (quantity) 250mcg/ml, 2.4ml
    on the pen. 60 x 10mcg = 600mcg???

    5mcg should equal .8333333u/ml, 10mcg =1.6u/ml, 15mcg would equal 2 1/2
    u/ml. Does that look right?

    100u = 3ml.

    Any ideas?


    Dave - 4:21:44 PM

    [Non-text portions of this message have been removed]

    Frances

  5. Dwain Palmer Says:

    Duh, OMG! Hey, my math was never in my brain and that’s why I’m having
    the problem figuring it out. Looks like Jodi proved it out by dispensing
    a 10mcg dose with the Byetta pen and then (her words) "lapping it up"
    with a syringe.

    Ok, the reason I’m asking. (This is not for the queasy). Since I was
    able to get on Lantus I have been refilling cartridges (3ml) for my
    Nova3 and Huma pens. I rinsed used Humalog and NPH cartridges with
    saline and have been refilling them for as long as Lantus was available.
    Now they have their own pen and cartridge so I will continue to do what
    I am doing because the Lantus/Aventis pen stinks big time.

    BTW, Aventis stated very clearly NOT to do what I am doing as any
    variation from their instructions would make the insulin no good. Bull..
    typical marketing hype. I’ve never had one problem and it has worked

    very well.

    So here I have with 4-10mcg Byetta pens and I need to reduce my evening
    shot to 5mcg. Reason being I have had two severe lows in the last couple
    of weeks. One being 28, the other 42!
    The 28 really freaked me out and I was hardly to able to do anything.
    Thankfully my wife reacted. It took from 11:30pm to 1:30pm to go from 28
    to 142 (she wouldn’t quit until then). I had 3 glasses of OJ laced with
    2-3 tablespoons of sugar, 5 glucose tabs, a gazzillion Oatmeal Raisin
    cookies and I *never* went over that 142! That was a solid low for sure.

    The dangerous part of it (other than the 28) is that at 11:00pm my BG
    was 102. at 11:30pm I was in a pool of sweat and my BG was 28. That’s a
    fast drop!! Most of my problem is probably due to weight loss and that
    I’m as low as I should be going (167lbs from 198).

    I thought I had the mccg - unit/cc figured out at .8333u representing
    5mcg. I have taken my trusty BD 1/2cc syringes and withdrew 20 units
    into the syringe. I have been injecting as close as I can to just under
    1 unit as I can and I have had no problems. Yes, reusing the syringe,
    nothing new for me. So according to Jodi I’ve been on the low side of
    the dose which is ok with me as long as I’m not over.

    I know that is says not to do that on the Byetta pen. Again, marketing
    hype. IMHO if I don’t mix the Byetta with anything else, and the
    transfer is sterile, I have no problem as with the Lantus. Of course if
    it changes color… :)
    I might even get frisky if things continue to go ok (been a week or so).
    I may take a cartridge from my BD Mini pen and refill that with Byetta.
    That does 1/2u dosing..

    Spirits of Ammonia anyone??

  6. Patricia Petty Says:

    <weaves into the room>
    <staggers to her chair>
    <sits there staring>

    Lol…Dave…

    Just teasing to be honest, I’ve wondered if there wasn’t some way that you
    could use a syringe to take out 7.5 mcg so you could take dose of between
    the 5 and the 10 pen. The 5 doesn’t seem to work as well for me, but the 10
    gives me lows. The only problem is I don’t use insulin so I have no access
    to needles and syringes. But for people that do….it might be a worthy
    experiment. And as long as the whole procedure is sterile I see no reason
    not to try it. But the important thing would be not to contaminant the
    medication. Which means NO REUSING the needles!!!!!! Lol….<shudders> How
    many units would the 7.5 mcg be? It’s been so long since pharmacology

    class!!!!! Let me see if I can get my old brain working here and see.
    DON’T tell me if you do reuse the needles to draw out the meds!!!!!

    Demetria-Beth

    Duh, OMG! Hey, my math was never in my brain and that’s why I’m having the
    problem figuring it out. Looks like Jodi proved it out by dispensing a 10mcg
    dose with the Byetta pen and then (her words) "lapping it up"
    with a syringe.

    Ok, the reason I’m asking. (This is not for the queasy). Since I was able to
    get on Lantus I have been refilling cartridges (3ml) for my
    Nova3 and Huma pens. I rinsed used Humalog and NPH cartridges with saline
    and have been refilling them for as long as Lantus was available.
    Now they have their own pen and cartridge so I will continue to do what I am
    doing because the Lantus/Aventis pen stinks big time.

    BTW, Aventis stated very clearly NOT to do what I am doing as any variation
    from their instructions would make the insulin no good. Bull..
    typical marketing hype. I’ve never had one problem and it has worked very
    well.

    So here I have with 4-10mcg Byetta pens and I need to reduce my evening shot
    to 5mcg. Reason being I have had two severe lows in the last couple of
    weeks. One being 28, the other 42!
    The 28 really freaked me out and I was hardly to able to do anything.
    Thankfully my wife reacted. It took from 11:30pm to 1:30pm to go from 28 to
    142 (she wouldn’t quit until then). I had 3 glasses of OJ laced with
    2-3 tablespoons of sugar, 5 glucose tabs, a gazzillion Oatmeal Raisin
    cookies and I *never* went over that 142! That was a solid low for sure.

    The dangerous part of it (other than the 28) is that at 11:00pm my BG was
    102. at 11:30pm I was in a pool of sweat and my BG was 28. That’s a fast
    drop!! Most of my problem is probably due to weight loss and that I’m as low
    as I should be going (167lbs from 198).

    I thought I had the mccg - unit/cc figured out at .8333u representing 5mcg.
    I have taken my trusty BD 1/2cc syringes and withdrew 20 units into the
    syringe. I have been injecting as close as I can to just under
    1 unit as I can and I have had no problems. Yes, reusing the syringe,
    nothing new for me. So according to Jodi I’ve been on the low side of the
    dose which is ok with me as long as I’m not over.

    I know that is says not to do that on the Byetta pen. Again, marketing hype.
    IMHO if I don’t mix the Byetta with anything else, and the transfer is
    sterile, I have no problem as with the Lantus. Of course if it changes
    color… :)
    I might even get frisky if things continue to go ok (been a week or so).
    I may take a cartridge from my BD Mini pen and refill that with Byetta.
    That does 1/2u dosing..

    Spirits of Ammonia anyone??

    [Non-text portions of this message have been removed]

  7. Dwain Palmer Says:

    7.5mcg converted to units might be helpful. Let us know what you work out.

    >>>DON’T tell me if you do reuse the needles to draw out the meds!!!!!

    Not me, I really wouldn’t reuse it for that.

  8. Patricia Petty Says:

    Hi Dave….

    This is what I have figured out so far….

    There are 100 units in a mL
    1000 mcg’s= 1 mg

    So 7.5 mcg’s = 0.0075 mgs

    Wait…I just looked at your calculations below….

    100 units =1 ml.

    So if 250 mcgs= 1 ml then


    250 mcg =100 units

    So, then dividing the units into the mcg’s you would come up with how many
    units in 1 mcg

    250 mcg /100 units= .4 units

    So there is .4 units per mcg.

    Then you would multiply this by 7.5 mcg (if that was the amount of the 10
    pen you wanted to take)

    .4 units X 7.5 mcg = 3

    7.5 mcg = 3 units.

    I think. Please don’t hold me to this it has been a long time since
    pharmacology class.

    Could someone more recent please give us some input?

    Demetria-Beth

    Duh, OMG! Hey, my math was never in my brain and that’s why I’m having the
    problem figuring it out. Looks like Jodi proved it out by dispensing a 10mcg
    dose with the Byetta pen and then (her words) "lapping it up"
    with a syringe.

    Ok, the reason I’m asking. (This is not for the queasy). Since I was able to
    get on Lantus I have been refilling cartridges (3ml) for my
    Nova3 and Huma pens. I rinsed used Humalog and NPH cartridges with saline
    and have been refilling them for as long as Lantus was available.
    Now they have their own pen and cartridge so I will continue to do what I am
    doing because the Lantus/Aventis pen stinks big time.

    BTW, Aventis stated very clearly NOT to do what I am doing as any variation
    from their instructions would make the insulin no good. Bull..
    typical marketing hype. I’ve never had one problem and it has worked very
    well.

    So here I have with 4-10mcg Byetta pens and I need to reduce my evening shot
    to 5mcg. Reason being I have had two severe lows in the last couple of
    weeks. One being 28, the other 42!
    The 28 really freaked me out and I was hardly to able to do anything.
    Thankfully my wife reacted. It took from 11:30pm to 1:30pm to go from 28 to
    142 (she wouldn’t quit until then). I had 3 glasses of OJ laced with
    2-3 tablespoons of sugar, 5 glucose tabs, a gazzillion Oatmeal Raisin
    cookies and I *never* went over that 142! That was a solid low for sure.

    The dangerous part of it (other than the 28) is that at 11:00pm my BG was
    102. at 11:30pm I was in a pool of sweat and my BG was 28. That’s a fast
    drop!! Most of my problem is probably due to weight loss and that I’m as low
    as I should be going (167lbs from 198).

    I thought I had the mccg - unit/cc figured out at .8333u representing 5mcg.
    I have taken my trusty BD 1/2cc syringes and withdrew 20 units into the
    syringe. I have been injecting as close as I can to just under
    1 unit as I can and I have had no problems. Yes, reusing the syringe,
    nothing new for me. So according to Jodi I’ve been on the low side of the
    dose which is ok with me as long as I’m not over.

    I know that is says not to do that on the Byetta pen. Again, marketing hype.
    IMHO if I don’t mix the Byetta with anything else, and the transfer is
    sterile, I have no problem as with the Lantus. Of course if it changes
    color… :)
    I might even get frisky if things continue to go ok (been a week or so).
    I may take a cartridge from my BD Mini pen and refill that with Byetta.
    That does 1/2u dosing..

    Spirits of Ammonia anyone??

    [Non-text portions of this message have been removed]

  9. Dwain Palmer Says:

    Great, thanks!

    So:

    5mcg = 2u
    7.5mcg = 3u
    10mcg = 4u

    What has really confused the issue for me is the Symlin web site where
    they say:

    If your dose amount is: Draw up this amount in syringe:
    15 micrograms 2 1/2 units
    30 micrograms 5 units


    45 micrograms 7 1/2 units
    60 micrograms 10 units

    They tell their patients to use 0.3ml (0.3cc size) to draw up and inject
    Symlin.

    I think the difference is in the syringes (mine are 1/2 cc) for U-100
    insulin-explains the difference in numbers, right?

  10. ramonita_1 Says:

    Hello Dave, If you give yourself a shot of the 10 dose but only press it
    down half way, pull the needle out and waste the remainder…would that
    work to give you approx. dose of 5?

    I don’t take insulin and I realise that Lantus is a long acting one but
    would decreasing your insulin dose help prevent lows?

    Aloha, Marge

  11. Dwain Palmer Says:

    Hi Marge. I don’t know if it would only release 1/2 that way. I’ll have
    to give that a test.

    As to decreasing the Lantus, I’ve gone from 28u at bedtime to 8u at
    bedtime. The only difference I can see is that my morning get up numbers
    are slightly higher.

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