Comments on: An important paper

By: Neva Marjory

Neva Marjory — Sat, 26 Nov 2005 10:01:40 +0000

"exercise (especially weight work-outs, machines, etc) that replaces fat
with muscle helps lower blood sugar, because muscle cells use insulin more
effectively than fat cells…(Or so my friendly neighboorhoon researcher
told me.)"

This is correct, all non-muscle cells require insulin to get glucose into
them for an energy source. Muscle cells at rest do also but when under a
moderate to hard load don’t require insulin to use glucose. In my
experience resistive exercise for about 7 minutes at the post meal glucose
peak can drop glucose up to 40 points. This makes muscle cells inherently
less insulin resistant as compared to all other types.

XB
IC|XC

By: Mercedes Tamela

Mercedes Tamela — Fri, 25 Nov 2005 20:56:17 +0000

I’m not sure I have this 100% percent right, but as I recall,
exercise (especially
weight work-outs, machines, etc) that replaces fat with muscle
helps lower
blood sugar, because muscle cells use insulin more effectively than
fat
cells…(Or so my friendly neighboorhoon researcher told me.)

Brian

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By: Neva Marjory

Neva Marjory — Thu, 24 Nov 2005 06:26:26 +0000

> A byetta user is handicapping themself if they don’t reduce food
intake, moderate carbs, and exercise so the drug has the best chance to
be most effective.
> XB
> IC|XC

POWERFUL WORDS! Thank you I needed to hear them! Although I have
been exercising more, my eating habits are getting worse.

Tami

By: keely2

keely2 — Thu, 24 Nov 2005 03:57:43 +0000

Thanks, XB. I’m sure it does have more to do with what I’m eating and how much
I’m moving than with the Byetta. Poor eating and exercising habits is what got
me to this point in the first place…as they say, can’t keep doing what I’ve
always done and expect different results. I appreciate your response. Kathy,
MN

"My average fasting bg over eight weeks is 131.5 and my postprandial bg has
averaged 103. It seems like most people have higher numbers after eating
than first thing in the morning. The average bg over eight weeks is 118,
so I’m high from the ideal 107 average for the A1C of 5. I figure the spit
really works for me at mealtime, but wears off after eight hours of sleep.
Maybe I’ll experiment with exercising just before bedtime — which will
probably keep me awake. But, if it helps… Thanks for any input. I’m
getting pretty frustrated about these numbers and my inability to lose
weight. I’m even considering gastric bypass. Kathy, MN."

It is unclear what the 131 is. It looks like you have dawn effect that
many diabetics have. When we awaken the body releases glucose from the
liver as an energy boost to get us started. In some diabetics there is an
overshoot in this and high morning numbers result.

First thing in the morning byetta has long since been removed from your
system. After an injection 1/2 of it is left after about 4.5 hours.
Exercise doesn’t cause problems with sleep. One approach some have tried
with dawn effect is to have a small snack before bed and to try fat or not,
carbs or not, etc. to see what might lower it. Some use insulin during the
night to control it.

Your numbers are not bad even with the dawn effect. Weight loss with
byetta is a side benefit only wwith some. If it works it is because it
blunts appetite, it has no magic weight effect in itself. So if you lose
weight it too will be because you decide to eat less. Exercise can help,
it does use some calories and also blunts appetite in some people but more
important it sets up the body to aid in weight loss and has many medical
benefits for a diabetic.

A byetta user is handicapping themself if they don’t reduce food intake,
moderate carbs, and exercise so the drug has the best chance to be most
effective.

XB
IC|XC